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WikiDoc is intended to be an educational tool, not a tool for any form of healthcare delivery. The educational content on WikiDoc drug pages is based upon the FDA package insert, National Library of Medicine content and practice guidelines / consensus statements. WikiDoc does not promote the administration of any medication or device that is not consistent with its labeling. Meclizine may interact with other medicines and supplements. Before taking meclizine, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
Meclizine Alcohol interaction
This activity discusses the various facets of meclizine, offering insights into its indications, mechanism of action, contraindications, interactions, and adverse events. Healthcare team members gain essential knowledge to proficiently manage patients with motion sickness and vertigo stemming from diverse underlying conditions. Other interprofessional healthcare team members, such as pharmacists, should collaborate with prescribers to guarantee that the patient understands proper administration, dosing, and knowledge of potential drug interactions. Clinical nurses should be aware of the adverse effects of the medication and monitor patients. All healthcare professionals must be aware of possible negative outcomes and work together to prevent, manage, and treat accordingly if such an event should occur. Interprofessional collaboration with open communication and shared decision-making will lead to successful outcomes when prescribing meclizine.
Side Effects
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use meclizine only for the indication prescribed. Take meclizine exactly as prescribed by your doctor.
- Tell your healthcare provider if you have any of these side effects that bother you.
- No effect of oral propantheline or atropine on blood alcohol levels was observed in healthy volunteers when administered before ingestion of a standard ethanol load.
- Alcohol, sedatives and tranquilizers can increase the drowsiness of the patient.
- Meclizine chewable tablets should be chewed or crushed completely before you swallow them.
- Meclizine is used to prevent nausea, vomiting, dizziness and motion sickness.
Does meclizine interact with other medicines (drug interactions)?
Meclizine has an onset of action of 30 to 60 minutes, depending on dosage; their duration of meclizine wikipedia action is 12 to 24 hours. The most common side effects of meclizine are listed below. Tell your healthcare provider if you have any of these side effects that bother you. Meclizine comes as a regular and chewable tablet and a capsule. For motion sickness, meclizine should be taken 1 hour before you start to travel. For dizziness caused by an ear condition, follow your doctor’s directions.
There is limited information regarding Patient Counseling Information of Meclizine in the drug label. There is limited information regarding Meclizine Storage in the drug label. There is limited information regarding Clinical Studies of Meclizine in the drug label.
FDA-Labeled Indications and Dosage (Adult)
Meclizine may be taken in the form of tablets, chewable tablets and capsules. When used to prevent motion sickness, they should be taken one hour before the beginning of the trip. Meclizine is an antihistamine, which acts as an antagonist of so-called H1 receptors.
- Histamine H1 receptors are expressed on the vestibular nuclei and nucleus of the solitary tract (NTS) that are activated by motion sickness and stimuli from the pharynx and stomach.
- Meclizine may be taken in the form of tablets, chewable tablets and capsules.
- When prescribing this medication, all healthcare practitioners should be aware of the common adverse reactions of the drug and the most susceptible population.
- It reduces the sensitivity of the labyrinthine apparatus.
- Drinking alcohol can increase certain side effects of meclizine.
Some meclizine tablets should not be chewed, crushed, or split. Ask your pharmacist if you are unsure how to take it. Meclizine chewable tablets should be chewed or crushed completely before you swallow them. People who are allergic to any of the following should not take meclizine.
Adverse Reactions
Before you take this medicine, tell your doctor if you have liver or kidney disease, asthma, glaucoma, an enlarged prostate, or urination problems. You should not take this medication if you are allergic to meclizine. Meclizine is a first-generation antihistamine (nonselective H1 antagonist) of the piperazine class. It is structurally and pharmacologically similar to buclizine, cyclizine, and hydroxyzine.
The lowest published toxic dose (TDLo) in rats via the oral route is 800 mg/kg. There is limited information regarding Off-Label Non–Guideline-Supported Use of Meclizine in pediatric patients. There is limited information regarding Off-Label Guideline-Supported Use of Meclizine in pediatric patients. There is limited information regarding FDA-Labeled Use of Meclizine in pediatric patients. There is limited information regarding Off-Label Guideline-Supported Use of Meclizine in adult patients. There are no known interactions between meclizine and foods or drinks.
Precautions with Alcohol
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if meclizine is right for you. Through its antagonistic action on the H1 receptors, meclizine primarily works by inhibiting signaling pathway transduction through histaminergic neurotransmission from the vestibular nuclei and NTS to the CTZ and medullary vomiting center. Meclizine may also decrease the labyrinth excitability and vestibular stimulation.